产品货号：
Z16148
中文名称：
FOXM1抗体
英文名称：
Anti-FOXM1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FOXM1 Antibody |
| 指标别名 | FKHL16;forkhead box M1;FOXM1;FOXM1B;HFH 11;HFH11;HNF 3;HNF 3/fork head homolog 11;INS 1;M phase phosphoprotein 2;MPHOSPH2;MPP 2;MPP2;PIG29;TGT3;Transcription factor Trident;TRIDENT;WIN |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ELISA,IP |
| 基因名称 | FOXM1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human FOXM1 recombinant protein (Position:Q457-P760). |
| 计算分子量 | 84KD |
| 实际分子量 | 100～110KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Forkhead box protein M1,also called FOXM1,is a protein that in humans is encoded by the FOXM1 gene.It is mapped to 12p13.33.The protein encoded by this gene is a member of the FOX family of transcription factors.FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation.FOXM1 gene is now known as a human proto-oncogene.Abnormal upregulation of FOXM1 is involved in the oncogenesis of basal cell carcinoma,the most common human cancer worldwide.It was hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion.What's more,FOXM1 has been shown to modulate the epigenome.It was found that overexpression of FOXM1 "brain washes" normal cells to adopt cancer-like epigenome. |
| Uniprot ID | Q08050 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | forkhead box M1 |
| 蛋白名全称 | Forkhead box protein M1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 ImmunoPrecipitation (IP) 1:50 ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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